Consuming foods rich in “sirtuin activators” — including red wine, kale, arugula, buckwheat, apples, blueberries, capers, red onions, walnuts, strawberries, extra virgin olive oil, parsley, dark chocolate, green tea, and coffee among others — will upregulate the expression of SIRT genes, increasing the producing sirtuin proteins that will retard the accumulation of fat. You’ve likely heard of the most famous of the sirtuin activators: Resveratrol, a compound found in red wine.
In 2003, David A. Sinclair, Ph.D., a professor in the Department of Genetics at Harvard Medical School, published the results of the first study to suggest that resveratrol slows aging in a way similar to calorie restriction — that is, by stimulating the SIRT2 gene, which promotes DNA stability, increases the production of the body’s own antioxidants, and puts the brakes on fat production. Since then, many more sirtuin activators (and the foods in which they’re found) have been identified in sirtfood science studies, and the list of potential benefits from consuming them keeps growing.
Potential Benefits of the Sirtfood Diet
Sirtuins have also been linked to the functioning of the nervous, cardiovascular, and immune systems, as well as liver, bone, muscle, stem cell, and tissue regeneration, according to 2014 article “The Controversial World of Sirtuins” published in the journal Drug Discovery Today: Technologies. Sirtuins have also been credited with helping to fight many age-related diseases, including cancer, cardiovascular disease, metabolic disorders, osteoporosis, neurodegenerative diseases, and arthritis.
Sirtfood science studies have also revealed that sirtuins can reduce inflammation, hypoxic stress (as might be caused by poor circulation), heat shock, and genotoxic (DNA damaging) stress, according to 2011 article “Sirtuins at a Glance” in the Journal of Cell Science, which notes that inflammation is a major cause of aging and aging-related diseases.
If this all sounds confusing, you can download the “Official Sirtfood Diet Planner” app from Google Play. The app kicks off your “Sirtification” with a “7-Day Sirtfood Challenge,” and includes a customizable shopping list, a weight loss tracker, a daily meal planner, and recipes that incorporate the top 20 sirtfoods. Participates who complete the challenge can move on to the 14-day maintenance phase.
Does the Sirtfood Diet Work?
So far, the diet has received ringing endorsements from many celebrities, most of whom are British, including (reportedly) Grammy-winning music artist Adele, model Jodie Kidd, TV cook Lorraine Pascale, boxers David Haye and Anthony Ogogo, Olympic sailor Ben Ainslie, and rugby player James Haskell.